If you have periodontal (gum) disease, tissue and root therapy is needed to help improve the health of your teeth and gums. Bacteria are the cause of gum disease. That’s why the doctors and hygienists may recommend ARESTIN®. It is an antibiotic that helps kill the bacteria at the root of the problem.

Getting treatment is painless

Your dental professional will place these microspheres into infected areas after completing your SRP. Getting ARESTIN® is painless. ARESTIN® will dissolve on its own, so no removal is required.

ARESTIN® is different from antibiotic pills

ARESTIN® is different from an antibiotic you take as a pill, because it’s placed right where you need it. A pill can’t give you the level of antibiotic concentration in your gums that ARESTIN® can.


  • Easily placed inside infected periodontal pockets just after completion of tissue and root therapy (scaling and root planing procedure).
  • Contains “Microspheres”-tiny, bead-like particles that are smaller than grains of sand and are not visible to the eye.
  • The Microspheres are filled with the antibiotic minocycline, and they release the drug over time into the infected periodontal pocket, killing bacteria that live there for up to twenty- one days.
  • The good news: many insurance plans are now providing some benefit for this procedure.

ARESTIN® Microspheres continue to fight the infection for up to 21 days after scaling and root planing.